Vic and Jack lean on one another as they process the loss of Dean while Ben and Bailey try to convince Dean's parents to allow them to raise Pru. Meanwhile at Station 23, Andy's role temporarily expands and Sullivan subs in. Carina and Maya explore growing their family.

With Adina's plan for world destruction reaching completion, and our heroes in the alternate world under attack, both sides must make great sacrifices if they are to save humanity.

With Adina's plan in motion, the world's last hope is for Bill to make one more journey, risking his own life in search of Catherine's help.

When the Pupa turns orange, Korvo realizes he left important Pupa information in his wallet on Shlorp. He and Terry travel back in time to the day they evacuated Shlorp, and knock Korvo's wallet into their spaceship. Returning to the present, they realize the Pupa merely ate something orange, but the time stream has been altered and they now live with Vanbo, an obnoxious Shlorpian. Returning to the past to set things right, Korvo and Terry learn they did not want each other as evacuation partners, but reconcile and beat up Vanbo. Yumyulack discovers Jesse has simulated a nicer version of himself in the "Pretend-O-Deck". His simulated self teaches him to be a better brother to Jesse, but one Yumyulack kills the other.

Young M.O.D.O.K. has kidnapped the family and replaced them with robots that trick M.O.D.O.K. into thinking Jodie wants him back. M.O.D.O.K. learns the truth and goes to free his real family. The family meet up inside the carnival-themed arena Murderworld, where young M.O.D.O.K. and Arcade reveal that each family member has two robotic replicas and that they must fight to the death, unsure of who is real or fake. Jodie goes toe-to-toe with Young M.O.D.O.K. The family leaves feeling united for the first time in a while.

Dinner Time! Korvo wins top prize at the annual neighborhood rib festival.

Catherine, Sophia and Nathan make their way to London, accompanied by Victor, a survivor encountered by chance. Along the way, the dangers multiply. Sacha's feelings towards Emily intensify and the young man's behavior becomes more and more disturbing. Feeling threatened, Bill is forced to flee.

The doctors must put aside their emotions under intense circumstances; Levi asks James a shocking question that could impact their future.

In the midst of a deadly heat wave, the team at Grey Sloan struggles to keep up with an overwhelming amount of patients; Amelia and Winston face a challenging surgery; Jo and Lucas run an errand for the hospital that takes an unexpected turn.

On one of Gabrielle's prison visits to see Carlos she creates a terrible riot, which lands Carlos in hot water. Also, Susan puts her feelings aside and joins Mike in searching for his son Zach. Lynette is surprised to find out that her son Parker has an imaginary friend. Lastly, George and Andrew both vie for Bree's attention as they both compete in making each other look bad in front of her, until one fight goes a little too far.

Susan's longtime book agent and dear friend, Lonny Moon gets into financial trouble. Lynette is forced to go out to bars night after night with her man-hungry boss, Nina. Bree finds out about Rex's feelings about her prior to his death. Lastly, Gabrielle hires hotshot lawyer David Bradley to defend Carlos in court but Carlos rejects him after he witnesses an attraction between David and Gabrielle.

Chastain is flooded with concert goers when a stampede at a music festival grounds leaves many in need of doctors. As Conrad and Nic race to help Josh Robinson, a professional adventure guide with a long list of prior injuries, Devon works with a musician who swears he is sober, even though his toxicology report suggests otherwise. Meanwhile, Bell stirs the pot when the hospital’s revered orthopedic surgeon, Dr. Kit Voss, demands a better resident, Julian works to get her boss on Bell’s good side and Winthrop continues to push Conrad to believe he’s a changed man.

The doctors must put aside their emotions under intense circumstances; Levi asks James a shocking question that could impact their future.

In the midst of a deadly heat wave, the team at Grey Sloan struggles to keep up with an overwhelming amount of patients; Amelia and Winston face a challenging surgery; Jo and Lucas run an errand for the hospital that takes an unexpected turn.

On one of Gabrielle's prison visits to see Carlos she creates a terrible riot, which lands Carlos in hot water. Also, Susan puts her feelings aside and joins Mike in searching for his son Zach. Lynette is surprised to find out that her son Parker has an imaginary friend. Lastly, George and Andrew both vie for Bree's attention as they both compete in making each other look bad in front of her, until one fight goes a little too far.

Susan's longtime book agent and dear friend, Lonny Moon gets into financial trouble. Lynette is forced to go out to bars night after night with her man-hungry boss, Nina. Bree finds out about Rex's feelings about her prior to his death. Lastly, Gabrielle hires hotshot lawyer David Bradley to defend Carlos in court but Carlos rejects him after he witnesses an attraction between David and Gabrielle.

A Station 19 firefighter lands in the emergency room for severe burn treatment; the team treats an elderly patient impaled by an art structure.

When Bell makes the executive call to utilize Julian Booth's medical devices, rather than the hospital's usual products, Kit and AJ must stop their momentary feuding in order to team up against him. Elsewhere in the hospital, Conrad and Nic work to make a child's dreams come true after finding out his cancer has returned and the rest of the staff takes notice of Julian and Devon's new friendship.

The aftermath of the convenience store shooting brings chaos to Grey Sloan; Ben hits a wall with his new emergency preparedness plan; romantic tensions surface for Owen; Amelia and Winston disagree over the surgical plan for a young patient.

Meredith and Nick return to Grey Sloan to treat a liver transplant patient; Bailey hosts an intern retreat at her home; Winston and Ben aid an unexpected crash victim.

Mike and Susan face a crisis in their relationship when Susan tries to get Paul Young arrested by confessing to a police officer that he killed Mrs. Huber and Mike has her diaries as proof. The officer goes over to Mike to get the story, but Mike denies the whole thing. As Carlos continues serving his jail sentence, Gabrielle valiantly tries to free him. Bree goes to a romantic hotel with George, but requests they sleep in separate rooms.

Gabrielle tries to revisit her past when old friends come to town, but doesn't want anyone to know that she's three months pregnant. With the aftermath of her breakup with Mike, Susan finds temporary solace from her ex-husband Karl as his relationship with Edie hits a bump. Also, the Scavos learn more about the new neighbors, the Harpers when they babysit their children and uncover a sex tape of the couple. Lastly, Caleb gets loose from the basement and roams around Wisteria Lane at night, which leads to major consequences for Gabrielle.

Vic and Jack lean on one another as they process the loss of Dean while Ben and Bailey try to convince Dean's parents to allow them to raise Pru. Meanwhile at Station 23, Andy's role temporarily expands and Sullivan subs in. Carina and Maya explore growing their family.

When a wealthy tycoon's much younger new wife, Julie Loeb, is shot at a family deer-hunting outing, suspects abound. The tycoon, Martin Loeb, is such a likely suspect that Megan openly accuses him and is fired from the case by Kate, at the request of the highly-influential Martin.

When a car careens out of control over an embankment, killing a middle-aged man in the driver's seat, Megan learns that all is not well on a pretty suburban cul-de-sac.

A Station 19 firefighter lands in the emergency room for severe burn treatment; the team treats an elderly patient impaled by an art structure.

The hunt for a counterfeit currency kingpin allows the team to get a glimpse into Villa’s past. Meanwhile, Rosie receives surprising news about his recent health issue.

When a wealthy tycoon's much younger new wife, Julie Loeb, is shot at a family deer-hunting outing, suspects abound. The tycoon, Martin Loeb, is such a likely suspect that Megan openly accuses him and is fired from the case by Kate, at the request of the highly-influential Martin.

A Station 19 firefighter lands in the emergency room for severe burn treatment; the team treats an elderly patient impaled by an art structure.

Vic and Jack lean on one another as they process the loss of Dean while Ben and Bailey try to convince Dean's parents to allow them to raise Pru. Meanwhile at Station 23, Andy's role temporarily expands and Sullivan subs in. Carina and Maya explore growing their family.

Mike and Susan face a crisis in their relationship when Susan tries to get Paul Young arrested by confessing to a police officer that he killed Mrs. Huber and Mike has her diaries as proof. The officer goes over to Mike to get the story, but Mike denies the whole thing. As Carlos continues serving his jail sentence, Gabrielle valiantly tries to free him. Bree goes to a romantic hotel with George, but requests they sleep in separate rooms.

George stalks Bree, despite her efforts to break up with him. Lynette takes charge of office politics. Carlos is paroled from prison and returns a new man, and Gabrielle is jealous of his new 'holier-than-thou' confidante. Susan meets her birth father and tries to begin a relationship with him.

Following a difficult case, the team faces the complexities of medical ethics; Bailey continues to navigate her working relationship with Ben; a group of college students on a scavenger hunt causes chaos around the hospital.

Meredith and Amelia prepare a funding proposal for their Alzheimer's research; Teddy and Owen hit a breaking point in their marriage; Jules has an awkward encounter with Dr. Beltran.

Halloween at Chastain proves to be just as spooky as ever when Conrad is tasked with diagnosing a young woman admitted to the hospital with extreme night terrors. Meanwhile, Devon faces his first Halloween in the ER, Nic panics over her decision to bring her newly sober sister to Mina's epic annual Halloween party and Bell finds an interesting way to make use of his new assistant.